There are some changes from 3.65 to 4.55 that need to be noted!
pkcs11 library
The name of the pkcs11 library changed. In 3.65 it was /usr/local/lib/libetpkcs11.so, in 4.55 it is /usr/lib/libeTPkcs11.so. Please note: in some documentations and howtos the libetpkcs11.so is referenced. Please change this according to libeTPkcs11.so, if you are using RTE 4.55.
eToken Password
The way the password is transferred to the eToken was optimized with RTE 4.x. This has the effect, that, if you initialize an eToken with RTE 4.55 you will not be able to use the eToken with RTE 3.65 - unless you choose the checkbox "initialize in 3.65 compatibility mode" when initializing the eToken.
Integration
In 4.55 there is no etokend anymore and you do not need have any udev script.
New Features
The RTE 4.55 now supports the eToken Pro Java card, FIPS and eToken Virtual.